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An AP-3-dependent pathway directs phagosome fusion with Rab8 and Rab11 vesicles involved in TLR2 signaling

by MAO | Oct 27, 2025 | Publications

Outer surface lipoproteins from the Lyme disease spirochete exploit the molecular switch mechanism of the complement protease C1s

by MAO | Oct 27, 2025 | Publications

The PD-1/PD-L1 pathway is induced during Borrelia burgdorferi infection and inhibits T cell joint infiltration without compromising bacterial clearance

by MAO | Oct 27, 2025 | Publications

Antiphospholipid autoantibodies in Lyme disease arise after scavenging of host phospholipids by Borrelia burgdorferi

by MAO | Oct 27, 2025 | Publications

Lipoproteome screening of the Lyme disease agent identifies inhibitors of antibody-mediated complement killing

by MAO | Oct 27, 2025 | Publications

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Recent Posts

  • My dog has better tick protection than I do. But that could change soon.
  • The explosion of ticks and alpha-gal syndrome
  • The Summer the Ticks Took Over
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  • Constantin “Nick” Takacs, Ph.D.

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The Tufts University Lyme Disease Initiative is a group of clinicians and scientists committed to working together to end Lyme disease as a threat to human health.  Taking a multi-pronged approach and partnering with researchers at other universities, in government and in industry, we are exploring unique strategies to meet our goal by the year 2030.  Visit our research pages to learn about our approaches to Lyme disease.

Recent Posts

My dog has better tick protection than I do. But that could change soon.

BBC: By Brianna Abbott. Tick populations are expanding their range throughout  Europe and the US , thanks to expanding...

The explosion of ticks and alpha-gal syndrome

CBS Sunday Morning: Did you know that Alpha-gal, which is short for galactose-α-1,3-galactose, is not new to the...

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