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Publications

Peromyscus leucopus, Mus musculus, and humans have distinct transcriptomic responses to larval Ixodes scapularis bites

by Linden Hu | Jan 21, 2026 | Publications

Infection and Immunity, Apr. 2025. Ixodes scapularis ticks are an important vector for at least seven tick-borne human p…

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Lipid scavenging by the Lyme disease spirochete Borrelia burgdorferi

by Linden Hu | Jan 21, 2026 | Publications

Plos Pathogens, Dec. 2025. Lyme disease is caused by the host-adapted spirochete Borrelia burgdorferi. With a genome of …

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Toll-like receptor 1 polymorphism is associated with impaired immune tolerance, dysregulated inflammatory responses to Borrelia burgdorferi, and heightened risk of post-infectious Lyme arthritis

by Linden Hu | Jan 21, 2026 | Publications

Frontiers in Immunology, Nov 2025. Introduction: Clinical presentation of Lyme disease is largely due to host immune res…

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Microbial genetic variation impacts host eco-immunological strategies and microparasite fitness in Lyme borreliae-reptile system

by Linden Hu | Jan 21, 2026 | Publications

Ticks and Tick-borne Diseases, Nov 2025. Tolerance and resistance are two host eco-immunological strategies in response …

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Guidance on the management of asymptomatic blood donors who test positive for Babesia

by Linden Hu | Jan 21, 2026 | Publications

Clinical Infectious Diseases, Dec 2025. Description: Babesiosis is a tick-borne disease that is endemic in the United St…

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Lyme Disease

by Linden Hu | Jan 21, 2026 | Publications

Annals of Internal Medicine 2025. Lyme disease, caused by Borrelia burgdorferi, is the most common vector-borne disease…

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The Tufts University Lyme Disease Initiative is a group of clinicians and scientists committed to working together to end Lyme disease as a threat to human health.  Taking a multi-pronged approach and partnering with researchers at other universities, in government and in industry, we are exploring unique strategies to meet our goal by the year 2030.  Visit our research pages to learn about our approaches to Lyme disease.

Recent Posts

Peromyscus leucopus, Mus musculus, and humans have distinct transcriptomic responses to larval Ixodes scapularis bites

Lipid scavenging by the Lyme disease spirochete Borrelia burgdorferi

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