Science Translational Medicine March 2025. Ixodes scapularis is a primary vector of tick-borne pathogens in North Americ…
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Hygromycin A Treatment of Borrelia burgdorferi-Infected Peromyscus leucopus Suggests Potential as a Reservoir-Targeted Antibiotic
Journal of Infectious Diseases, 2026. Lyme disease spirochetes are maintained in natural reservoirs before spilling ove…
Increasing Risk for Tick-Borne Disease: What Should Clinicians Know?
Many of the diverse tick-borne diseases (TBD) in the US appear to be increasing in incidence, leading to concern that fa…
Powassan virus persistence after acute infection
Survivors of Powassan encephalitis often have persistent neurological disease. A new mouse model replicates some…
Comparative reservoir competence of Peromyscus leucopus, C57BL/6J, and C3H/HeN for Borrelia burgdorferi B31
Although laboratory strains of Mus musculus mice have successfully been leveraged to model acute human Lyme disease,…
Borrelia burgdorferi initiates early transcriptional re-programming in macrophages that supports long-term suppression of inflammation
Borrelia burgdorferi (Bb), the causative agent of Lyme disease, establishes a long-term infection and leads to disease…
