Lyme disease is caused by the bacterial pathogen Borrelia burgdorferi, which can be readily modeled in laboratory…
Emerging and re-emerging pathogens often stem from zoonotic origins, cycling between humans and animals, and are…
Modern infectious disease outbreaks often involve changes in host tropism, the preferential adaptation of pathogens to…
Lyme disease is the most common vector-borne disease in North America and Europe. The clinical manifestations of Lyme…
Intracellular compartmentalization of ligands, receptors and signaling molecules has been recognized as an important…
Proteolytic cascades comprise several important physiological systems, including a primary arm of innate immunity…