Although laboratory strains of Mus musculus mice have successfully been leveraged to model acute human Lyme disease,...
Comparative reservoir competence of Peromyscus leucopus, C57BL/6J, and C3H/HeN for Borrelia burgdorferi B31
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Borrelia burgdorferi initiates early transcriptional re-programming in macrophages that supports long-term suppression of inflammation
Borrelia burgdorferi (Bb), the causative agent of Lyme disease, establishes a long-term infection and leads to disease...
Single-cell RNA sequencing of murine ankle joints over time reveals distinct transcriptional changes following Borrelia burgdorferi infection
Lyme disease is caused by the bacterial pathogen Borrelia burgdorferi, which can be readily modeled in laboratory...
Lizards and the enzootic cycle of Borrelia burgdorferi sensu lato
Emerging and re-emerging pathogens often stem from zoonotic origins, cycling between humans and animals, and are...
Structural evolution of an immune evasion determinant shapes pathogen host tropism
Modern infectious disease outbreaks often involve changes in host tropism, the preferential adaptation of pathogens to...
Whole genome sequencing of human Borrelia burgdorferi isolates reveals linked blocks of accessory genome elements located on plasmids and associated with human dissemination
Lyme disease is the most common vector-borne disease in North America and Europe. The clinical manifestations of Lyme...