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Publications

A Selective Antibiotic for Lyme Disease

by MAO | Oct 27, 2025 | Publications

Lyme disease is on the rise. Caused by a spirochete Borreliella burgdorferi, it affects an estimated 500,000 people in...

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Lyme Carditis in Hospitalized Children and Adults, a Case Series

by MAO | Oct 27, 2025 | Publications

Ten children and 20 adults were admitted for Lyme carditis between June and October. Ninety percent were male, and 87%...

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Development of a Capture Sequencing Assay for Enhanced Detection and Genotyping of Tick-borne pathogens

by MAO | Oct 27, 2025 | Publications

Inadequate sensitivity has been the primary limitation for implementing high-throughput sequencing for studies of...

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Powassan Virus Encephalitis Following Brief Attachment of Connecticut Deer Ticks

by MAO | Oct 27, 2025 | Publications

Powassan virus (POWV) is a tick-transmitted pathogen that may cause severe encephalitis; experimentally, it can be...

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Blocking Borrelia burgdorferi Transmission from Infected Ticks to Nonhuman Primates with a Human Monoclonal Antibody

by MAO | Oct 27, 2025 | Publications

Disrupting transmission of Borrelia burgdorferi sensu lato complex (B. burgdorferi) from infected ticks to humans is...

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Semicentennial of Human Babesiosis, Nantucket Island

by MAO | Oct 27, 2025 | Publications

Semicentennial of Human Babesiosis, Nantucket Island Fifty years ago, the index case of human babesiosis due to...

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The Tufts University Lyme Disease Initiative is a group of clinicians and scientists committed to working together to end Lyme disease as a threat to human health.  Taking a multi-pronged approach and partnering with researchers at other universities, in government and in industry, we are exploring unique strategies to meet our goal by the year 2030.  Visit our research pages to learn about our approaches to Lyme disease.

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