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Publications

Design of a broadly reactive Lyme disease vaccine

by MAO | Oct 27, 2025 | Publications

Design of a broadly reactive Lyme disease vaccine We designed a six component vaccine that elicits antibody (Ab)…

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Host Metabolic Response in Early Lyme Disease

by MAO | Oct 27, 2025 | Publications

Host Metabolic Response in Early Lyme Disease Metabolic biosignatures of patients with early Lyme disease can…

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Post-treatment Lyme disease symptoms score: Developing a new tool for research

by MAO | Oct 27, 2025 | Publications

Post-treatment Lyme disease symptoms score: Developing a new tool for research Some patients have residual…

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Genome-wide screen identifies novel genes required for Borrelia burgdorferi survival in its Ixodes tick vector

by MAO | Oct 27, 2025 | Publications

Genome-wide screen identifies novel genes required for Borrelia burgdorferi survival in its Ixodes tick vector To…

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Anti-OspA DNA-Encoded Monoclonal Antibody Prevents Transmission of Spirochetes in Tick Challenge Providing Sterilizing Immunity in Mice

by MAO | Oct 27, 2025 | Publications

Anti-OspA DNA-Encoded Monoclonal Antibody Prevents Transmission of Spirochetes in Tick Challenge Providing Sterilizing…

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Surge in Anaplasmosis Cases in Maine, USA, 2013-2017

by MAO | Oct 27, 2025 | Publications

Surge in Anaplasmosis Cases in Maine, USA, 2013-2017 Incidence of human granulocytic anaplasmosis is rising in Maine,…

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  • About-us
    • History
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The Tufts University Lyme Disease Initiative is a group of clinicians and scientists committed to working together to end Lyme disease as a threat to human health.  Taking a multi-pronged approach and partnering with researchers at other universities, in government and in industry, we are exploring unique strategies to meet our goal by the year 2030.  Visit our research pages to learn about our approaches to Lyme disease.

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Single-cell RNA sequencing of murine ankle joints over time reveals distinct transcriptional changes following Borrelia burgdorferi infection

Lizards and the enzootic cycle of Borrelia burgdorferi sensu lato

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